1
general::
Abundantly supplied, as in He's lousy with money. Like LOUSE UP, this expression alludes to being infested with lice. [First half of 1800s]
American Heritage Idioms
2
general::
Phrase(s): lousy with someone or something
Inf. having lots of someone or something. (Like an infestation of lice.) • Old Mr. Wilson is lousy with money. • Tiffany is lousy with jewels and furs, but she’s got bad teeth.
McGrawhill's American Idioms And Phrasal Verbs